Take Viagra for instance. This is a drug that was being tested to help with angina, but a different disorder was helped with the little blue pill.
Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer’s Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). The first clinical trials were conducted in Morriston Hospital in Swansea.[1] Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections.[2][3] Pfizer therefore decided to market it for erectile dysfunction, rather than for angina. The drug was patented in 1996, approved for use in erectile dysfunction by the US Food and Drug Administration on March 27, 1998, becoming the first oral treatment approved to treat erectile dysfunction in the United States, and offered for sale in the United States later that year.
So, you’d think that when it comes to female Viagra, science would know what it’s doing. Wrong.
The first pill designed to boost the female sex drive failed to make a significant impact on libido in two studies, federal health regulators said, though some women did report slightly more sexually satisfying experiences.
The Food and Drug Administration is considering Boehringer Ingelheim‘s drug flibanserin for premenopausal women who report a lack of sexual desire, a market that drugmakers have been targeting for more than a decade since the blockbuster success of Viagra in men.
The search for so-called “female Viagra,” has proved elusive though, with many drugs abandoned after showing lackluster results.
You know what I think it is? Society doesn’t want women to enjoy sex when they reach their “Golden Girls” years. If scientists can accidentally extend the erection, they can’t purposely find a way to boost the female libido?
This article appears in Jun 15-21, 2010.
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An on-line post which was reviewed by the Glickman Urological Institute of the Cleveland Clinic also reported on other oral medicines that are under analysis Uprima used in Europe, but is pending US approval, Topiglan a cream applied on the penis, Avanafil an inhibitor, and Melanocortin activators these act by way of the central nervous method.